Clostridium perfringens Bacteremia in a Peritoneal Dialysis Patient: Clinical Implications

Clostridial species bacteremia rarely occurs in general population. Usually hosts with organic gastrointestinal lesion or immunocompromised background are more likely to contract this disease. We present a case of Clostridium perfringens bacteremia in an end-stage renal disease patient undergoing peritoneal dialysis, without other underlying disease. The role of uremia and associated dialytic therapy in mediating this infrequent infection among the end-stage renal disease population was discussed, with relevant reports provided. Our patient also displayed infrequent manifestation of Clostridium perfringens sepsis and severe anemia. Several potential mechanisms were also suggested. According to the current finding, it is then imperative for us to reconsider end-stage renal disease as an immunocompromised